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Accutane can create severe, life-threatening birth defects if the mother takes the treatment during pregnancy. Even one dose of Accutane can cause major birth defects of the baby’s ears, eyes, face, skull, heart, as well as brain. Never use Accutane if you are pregnant.
For Women: Unless you have had your uterus and ovaries removed (total hysterectomy) or have been in menopause for at least 12 months in a row, you are considered to be of child-bearing potential.

Even women who have had their tubes tied are required to use birth control while taking Accutane.

You must have a negative pregnancy test 30 days before you get started taking Accutane. A pregnancy test is also required immediately before each prescription is refilled, good after you take your last dose of Accutane, as well as again 30 days later. All pregnancy testing is required by the iPLEDGE program.

You must agree in writing to use two specific forms of birth control beginning 30 days before you start taking Accutane as well as ending 30 days after you stop taking it. Both a primary and also a secondary form of birth control must be used together.

Primary forms of birth control include:

– tubal ligation (tubes tied);
– vasectomy of the male sexual partner;
– an IUD (intrauterine device);
– estrogen-containing birth control pills (not mini-pills);
– as well as hormonal birth control patches, implants, injections, or vaginal ring.

Secondary forms of birth control include:

– a male latex condom plus spermicidal foam or gel;
– a diaphragm plus spermicidal foam or gel;
– a cervical cap plus spermicidal foam or gel; as well as
– a vaginal sponge containing spermicide.

Do not take St. John’s wort, an herbal supplement, if you are Using any types of hormonal birth control, including pills, patches, implants, injections, or a vaginal ring. Breakthrough bleeding may take place.
Stop Using Accutane as well as call your doctor at once if you have unprotected sex, if you quit Using birth control, if your period is late, or if you think you might be pregnant.

It is not identified whether Accutane passes into breast milk. Do not take Accutane without first talking to your doctor if you are breast-feeding a baby.

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